Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFM1 All Species: 53.03
Human Site: S452 Identified Species: 89.74
UniProt: Q96RP9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RP9 NP_079272.4 751 83471 S452 H V P D P V I S I A M K P S N
Chimpanzee Pan troglodytes XP_001154618 751 83449 S452 H V P D P V I S I A M K P S N
Rhesus Macaque Macaca mulatta XP_001094832 770 85971 S471 H V P D P V I S I A M K P S N
Dog Lupus familis XP_534320 771 85436 S472 H V P D P V I S I A M K P S N
Cat Felis silvestris
Mouse Mus musculus Q8K0D5 751 83531 S452 H V P E P V I S I A M R P S N
Rat Rattus norvegicus Q07803 751 83439 S452 H V P D P V I S V A M K P S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233639 738 82390 S439 H V P D P V I S V A M K P S N
Frog Xenopus laevis A5PKR8 748 83504 S449 H V P D P V I S V S M K P T N
Zebra Danio Brachydanio rerio Q08BB1 745 82731 S446 H V P E P V I S M A I R P S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM33 745 83491 S446 F V P E P V V S M A I K P N N
Honey Bee Apis mellifera XP_394825 744 84514 S449 Y I P E P V V S M S L Q L K N
Nematode Worm Caenorhab. elegans Q9XV52 750 83636 S449 H I P E P V I S M A I K P V N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C641 754 83160 S464 N V P E P V M S L A V Q P V S
Baker's Yeast Sacchar. cerevisiae P25039 761 84555 V472 M Y V P D A V V S L S I T P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.6 88.9 N.A. 90.4 90.4 N.A. N.A. 81.3 80.2 78 N.A. 65.1 61.9 55.2 N.A.
Protein Similarity: 100 100 96.4 93.9 N.A. 94.8 95.2 N.A. N.A. 90.5 89.7 89.8 N.A. 78.8 77.2 71.3 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. N.A. 93.3 80 73.3 N.A. 60 33.3 66.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 93.3 86.6 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 53.7 53.4 N.A.
Protein Similarity: N.A. N.A. N.A. 70.2 70.5 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 79 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 72 0 36 0 22 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 65 0 8 0 % K
% Leu: 0 0 0 0 0 0 0 0 8 8 8 0 8 0 0 % L
% Met: 8 0 0 0 0 0 8 0 29 0 58 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 93 % N
% Pro: 0 0 93 8 93 0 0 0 0 0 0 0 86 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 93 8 15 8 0 0 58 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % T
% Val: 0 79 8 0 0 93 22 8 22 0 8 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _